How can artificial intelligence help prioritize particularly vulnerable patients?

A new AI algorithm can give doctors and nurses more peace of mind. The algorithm can predict critical illness.

In the future, doctors and nurses will be less likely to miss signs of lung or heart failure. A new algorithm can predict a number of critical illnesses, which will give doctors peace of mind and relieve pressure.

This is the opinion of Ulf Hørlyck, senior consultant at the Emergency Department at the Regional Hospital in Horsens.

- The algorithm is the most innovative thing I've seen in a long time - from an employee safety perspective," says Ulf Hørlyk.

Detect critical illness earlier

The AI algorithm +Priocritical has just been tested at Horsens Regional Hospital. The researchers behind the algorithm state in an article that the algorithm clearly outperforms traditional methods for diagnosing, for example, sepsis (blood poisoning). In addition, the thesis is that the algorithm can detect critical illness earlier than traditional methods, which will mean a high quality improvement for patients.

The algorithm is incorporated into a smartphone app. The app constantly collects data, and the employee receives a notification if the data shows an increased risk of a number of critical illnesses, explains healthcare engineer Simon Meyer Lauritsen.

- As soon as a new blood sample is analyzed or a vital parameter is measured, the new data is collected so that the risk assessment is constantly updated. The app also provides the objective data so the doctor or nurse can see the reason why the notification is sent, says Simon Meyer Lauritsen.

+Priocritical is a further development of Simon Meyer Lauritsen's PhD thesis. He has based his algorithm development on historical data from the data project CROSS TRACK in a business PhD program in close collaboration with the company Enversion A/S, Horsens Regional Hospital and Aarhus University.

New opportunities for AI tools

Gitte Kjeldsen, Danish Life Science Cluster, is the project manager for the AI Signature project where the algorithm was developed.

- We are excited to leverage the clinical data and further develop Simon's research-based work into a concrete solution. This algorithm brings a new perspective to AI-driven decision support tools and opens up new, broader solutions in early detection with AI," says Gitte Kjeldsen. She adds:

- One of the major challenges in healthcare is to transform academic knowledge into concrete, usable tools for healthcare professionals, and we have succeeded in doing so to the benefit of all.

Interdisciplinarity is indispensable

The partners have just completed a three-week design sprint with +Priocritical with interactions at the Regional Hospital in Horsens. The Emergency Department, Medical Department and Anesthesiology Department contributed with medical, nursing and management skills.

The development work has also involved anthropologists, UX designers, researchers and data engineers.

The feedback from healthcare professionals has been hugely positive.

This interdisciplinarity should be the basis for all healthcare innovation, and in the development of AI solutions, interdisciplinarity is simply indispensable, says Simon Meyer Lauritsen.

- Feedback from the clinic is indispensable for us technicians. We need to know what features they need and how a device adds the most value. Researchers and healthcare professionals work in two very different scenarios, so we need to come together to understand each other's challenges. I'm proud that my geekiness has resulted in a workable solution, but we've only gotten this far because of the support of healthcare professionals," says Simon Meyer Lauritsen.

The next steps in the project will be to customize the algorithm and test it in the clinic with real-time data, so work is underway to create the optimal framework for this.

Facts:

  • The algorithm is being further developed and tested in a project supported by digital AI signature funds.
  • Danish Life Science Cluster is the project manager for the project TVÆRSPOR, which uses health data to support more individualized treatment pathways, better prevention and develop and implement decision support models in the healthcare system (www.tværspor.dk).
  • Simon Lauritsen's industrial PhD thesis was prepared in collaboration with the company Enversion A/S, Horsens Regional Hospital and Aarhus University.
  • Publications:
  • The Framing of machine learning risk prediction models illustrated by evaluation of sepsis in general wards. npj Digital Medicine, Vol. 4, 158, 11.2021
  • Explainable artificial intelligence model to predict acute critical illness from electronic health records. Nature Communications, Vol. 11, 3852, 07.2020
  • Early detection of sepsis utilizing deep learning on electronic health record event sequences./ Lauritsen, Simon MeyerKalør, Mads Ellersgaard; Kongsgaard, Emil Lund; Lauritsen, Katrine MeyerJørgensen, Marianne JohanssonLange, JeppeThiesson, Bo.
  • In: Artificial Intelligence in Medicine, Volume 104, 101820, 04.2020.

Participants in the project